CRISPR/Cas systems in archaea
نویسندگان
چکیده
منابع مشابه
CRISPR/Cas systems in archaea
CRISPR (Clustered, Regularly, Interspaced, Short, Palindromic Repeats) loci have been shown to provide prokaryotes with an adaptive immunity against viruses and plasmids. CRISPR arrays are transcribed and processed into small CRISPR RNA molecules, which base-pair with invading DNA or RNA and lead to its degradation by CRISPR-associated (Cas) protein complexes. New spacers can be acquired by act...
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CRISPR adaptive immune systems were analyzed for all available completed genomes of archaea, which included representatives of each of the main archaeal phyla. Initially, all proteins encoded within, and proximal to, CRISPR-cas loci were clustered and analyzed using a profile-profile approach. Then cas genes were assigned to gene cassettes and to functional modules for adaptation and interferen...
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ژورنال
عنوان ژورنال: Mobile Genetic Elements
سال: 2012
ISSN: 2159-256X
DOI: 10.4161/mge.19907